Nos publications majeures

Acta Diabetologica

Marciniak et al. Differential unfolded protein response in skeletal muscle from non-diabetic glucose tolerant or intolerant patients with obesity before and after bariatric surgery. Acta Diabetol 2020, 57: 819-826.

https://pubmed.ncbi.nlm.nih.gov/32086613/

American Diabetes Association Logo

de Toledo M, Lopez-Mejia IC, Cavelier P, Pratlong M, Barrachina C, Gromada X, Annicotte JS, Tazi J, Chavey C. Lamin C Counteracts Glucose Intolerance in Aging, Obesity, and Diabetes Through β-Cell Adaptation. 2020, 69(4):647-660.

https://diabetes.diabetesjournals.org/content/69/4/647

Transcriptional network analysis implicates altered hepatic immune function in NASH development and
resolution. Nature Metab., june 2019 ; 1, 604-614Haas J.T., Vonghia L., Mogilenko D.A., errijken A., Molendi-Coste O.,
Fleury S., Deprince A., Nikitin A., Woitrain E., Ducrocq-Geoffroy L., Pic S., Derudas B., Dehondt H., Gheeraert C., Van Gaal L.,
Driessen A., Lefebvre P., Staels B., Francque S., Dombrowicz D.:

https://pubmed.ncbi.nlm.nih.gov/31701087/

Factor and Management of Heart Valve Disease, JACC ,march 12 2019, 73, 1078- 88E. Van Belle, F. Vincent, A.
Rauch, C. Casari, E. Jeanpierre, V. Loobuyck, M. Rosa, C. Delhaye, H. Spillemaeker, C. Paris, N. Debry, B. Verdier, A. Vincentelli,
A. Dupont, P. J. Lenting, S. Susen. : von Willebrand

https://www.jacc.org/doi/full/10.1016/j.jacc.2018.12.045

Metabolic and innate immune cues merge into a specific inflammatory response via the UPR. Cell, may 16
2019 ; 177, 1201-1216 Mogilenko D.A., Haas J.T., Lhomme L., Fleury S., Quemener S., Levavasseur M., Becquart C., Wartelle
J., Bogomolova A, Pineau L., Molendi-Coste O., Lancel S., Dehondt H., Gheeraert C., Melchior A., Dewas C., Nikitin A., Pic S.,
Rabhi N., Annicotte J.S., Oyadomari S., Velasco-Hernandez T., Cammenga J., Foretz M., Viollet B., Vukovic M., Villacreces A.,
Kranc K., Carmeliet P., Marot G., Boulter A., Tavernier S., Berod L., Longhi M.P., Paget C., Janssens S., Staumont-Salle D., Aksoy
E., Staels B., Dombrowicz D.:

https://pubmed.ncbi.nlm.nih.gov/31031005/

Hepatic transcriptomic signatures of statin treatment are associated with impaired glucose homeostasis in
severely obese patients. BMC Med.Genomics, june 3 2019 ; 12, 80Margerie D., Lefebvre P., Raverdy V., Schwahn U.,
Ruetten H., Larsen P., Duhamel A., Labreuche J., Thuillier D., Derudas B., Gheeraert C., Dehondt H., Dhalluin Q., Alexandre J.,
Caiazzo R., Nesslany P., Verkindt H., Pattou F., Staels B.:

https://pubmed.ncbi.nlm.nih.gov/31159817/

Glycogen dynamics drives lipid droplet biogenesis during brown adipocyte differentiation. Cell Rep. , november 5 2019, 29:1410-1418 Mayeuf-Louchart A., Lancel S., Sebti Y., Pourcet B., Loyens A., Delhaye S., Duhem C., Beauchamp J., Ferri L., Thorel Q., Boulinguiez A., Zecchin M., Dubois-Chevalier J., Eeckhoute J., Vaughn L.T., Roach P.J., Dani C., Pederson B.A., Vincent S.D., Staels B., Duez H

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057258/

Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and
hypertension. Nat Med. 2019 Nov ;25(11) :1733-1738. Baron M, Maillet J, Huyvaert M, Dechaume A, Boutry R, Loiselle H,
Durand E, Toussaint B, Vaillant E, Philippe J, Thomas J, Ghulam A, Franc S, Charpentier G, Borys JM, Lévy-Marchal C, Tauber M,
Scharfmann R, Weill J, Aubert C, Kerr-Conte J, Pattou F, Roussel R, Balkau B, Marre M, Boissel M, Derhourhi M, Gaget S, Canouil
M, Froguel P, Bonnefond A.

https://pubmed.ncbi.nlm.nih.gov/31700171/

The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain
regions involved in addiction and reward. Ndiaye FK, Huyvaert M, Ortalli A, Canouil M, Lecoeur C, Verbanck M, Lobbens S,
Khamis A, Marselli L, Marchetti P, Kerr-Conte J, Pattou F, Marre M, Roussel R, Balkau B, Froguel P, Bonnefond A. Int J Obes
(Lond). 2020 Feb;44(2):539-543.

https://pubmed.ncbi.nlm.nih.gov/31388097/

MOLECULAR METABOLISM LOGO

Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2
diabetes. Mol Metab. 2019 Jun;24:98-107 Khamis A, Canouil M, Siddiq A, Crouch H, Falchi M, Bulow MV, Ehehalt F, Marselli
L, Distler M, Richter D, Weitz J, Bokvist K, Xenarios I, Thorens B, Schulte AM, Ibberson M, Bonnefond A, Marchetti P Solimena M, Froguel P.

https://pubmed.ncbi.nlm.nih.gov/30956117/

American Diabetes Association Logo

Inter-Individual Heterogeneity of SGLT2 Expression and Function in Human Pancreatic Islets.
Saponaro C, Mühlemann M, Acosta-Montalvo A, Piron A, Gmyr V, Delalleau N, Moerman E, Thévenet J, Pasquetti G, Coddeville A, Cnop M, Kerr-Conte J, Staels B, Pattou F, Bonner C.Diabetes. 2020 Jan 2. pii: db190888. doi: 10.2337/db19-0888.

https://diabetes.diabetesjournals.org/content/69/5/902

American Diabetes Association Logo

Ten-Year Outcome of Islet Alone or Islet After Kidney Transplantation in Type 1 Diabetes: A Prospective Parallel-Arm
Cohort Study.Vantyghem MC, Chetboun M, Gmyr V, Jannin A, Espiard S, Le Mapihan K, Raverdy V, Delalleau N, Machuron F,
Hubert T, Frimat M, Van Belle E, Hazzan M, Pigny P, Noel C, Caiazzo R, Kerr-Conte J, Pattou F; Members of the Spanish Back
Pain Research Network Task Force for the Improvement of Inter-Disciplinary Management of Spinal Metastasis.Diabetes Care. 2019 Nov; 42(11):2042-2049. doi: 10.2337/dc19-0401

https://care.diabetesjournals.org/content/42/11/2042